Large-scale gene trapping in C57BL/6N mouse embryonic stem cells
نویسندگان
چکیده
منابع مشابه
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
We report the construction and analysis of a mouse gene trap mutant resource created in the C57BL/6N genetic background containing more than 350,000 sequence-tagged embryonic stem (ES) cell clones. We also demonstrate the ability of these ES cell clones to contribute to the germline and produce knockout mice. Each mutant clone is identified by a genomic sequence tag representing the exact inser...
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ژورنال
عنوان ژورنال: Genome Research
سال: 2008
ISSN: 1088-9051
DOI: 10.1101/gr.078352.108